Fanconi Syndrome

Fanconi Syndrome is related to kidney malfunction leading to excessive urine production and excessive thirst which results in deficits of water, calcium, potassium, magnesium and other substances in the body.

This is a disorder in which the proximal renal tubules of the kidney do not properly reabsorb electrolytes and nutrients back into the body, but instead "spill" them in the urine.

If left untreated, an affected dog will generally die from the disorder. If caught early, affected dogs can do well on treatment.

The onset is typically between four and eight years of age, although onsets as early as three years and as late as ten years have occurred. The mode of inheritance is not known, but it is generally agreed to be an inherited problem in Basenjis. This is a significant disorder in the Basenji breed, affecting 10% or more of dogs. It is also seen in the Norwegian Elkhound, Shetland Sheepdog, and Schnauzer.

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