Storage Disease (GM1)
This is a recessive genetic disorder caused by the lack of an enzyme that allows a build-up of toxic substances in the nerve cells. Puppies are generally tested at 7-8 weeks of age unless both parents are litter-tested or ancestor-tested to be normal. An affected puppy will eventually die or need to be euthanized, usually within the first year of life. Carrier puppies will live normal lives; however, they have the potential to pass the disorder on to their offspring if bred. In 1999, a new DNA-based test became available for Storage Disease and it is recommended that all breeding dogs be DNA tested.
Note: This section of the Canada's Guide to Dogs website is intended as a source of information only. It is not intended as a substitute for professional care. Always consult with your Veterinarian about health related matters.